3- Amino-2-hydroxybutyric acids

Amino-3-hydroxybutyric acid [924-49-2] M 119.1, m ZlS fdec). Crystd from H2O or aqueous EtOH. 

AS Gopalan, CJ Sih. Bifunctional chiral synthons via biochemical methods. 5. Preparation of (S)-ethyl hydrogen-3-hydroxyglutarate, key intermediate to (R)-4-amino-3-hydroxybutyric acid and L-carnitine. Tetrahedron Lett 25 5235-5238, 1984. 

Amino-3-hydroxybutyric Acid Trimethylbetaine Levocarnitine 4-Trimethylamino-3-hydroxybutyrate (/ )-3-Carboxy-2-hydroxy-/V,/V,/V-trimethyl-1 -propanaminium Hydroxide, Inner Salt... 

Amino-3-hydroxybutyric Acid Trimethylbetaine, (S2)5 DL-2-Amino-3-hydroxypropanoic Acid,... 

C4H9N03 DL-4 amino-3-hydroxybutyric acid 924-49-2 22.50 1.0765 2 3996 C4H11NO N-ethyl-N-hydroxyethanamine 3710-84-7 -25.50 1.0697 2... 

Synthetic applications of AD which have already appeared and which are of potential industrial interest include the synthesis of propranolol (9) [48], diltiazem (10) [49], carnitine, and 4-amino-3-hydroxybutyric acid (11) [50], azole anti-fungals (12) [51], chloramphenicol (13) [52], reticuline intermediates (14) [53], camptothecin analogs (15) [54], khellactone (16) derivatives [55], taxol C-13 side chain (17) [56], halosarin [64], dehydro- xo-brevicomin [65], and antimalar-ial active cyclopenteno-l,2,4-trioxanes [57], as summarized in Figure 4. 

K. Bock, I. Lundt, and C. Pedersen, Synthesis of S- and R-4-amino-3-hydroxybutyric acid (GABOB) and S- and R-camitine from arabinose or ascorbic acid, Acta Chem. Scand, B37 (1983) 341-344. 

Desymmetrization of S-hydroxyglutaronitrile 17 toward (l9-4-cyano-3-hydroxybutyric acid 18, a key intermediate in the synthesis of Atorvastalin 19, L-Camitine 20 and (/ )-4-amino-3-hydroxybutyric acid (GABOB, 21) [29,30. ... 

Amino-2-hydroxybutyric acid, A9.4 4-Amino-3-hydroxybutyric acid, A2.16 Allothreonine, A24.2 Homoserine, A 5.7... 

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