Amino acid representative

Some of the most important organic compounds in biochemistry are the a-amino acids, represented by the general formula shown. 

Amino acid separations represent another specific application of the technology. Amino acids are important synthesis precursors - in particular for pharmaceuticals -such as, for example, D-phenylglycine or D-parahydroxyphenylglycine in the preparation of semisynthetic penicillins. They are also used for other chiral fine chemicals and for incorporation into modified biologically active peptides. Since the unnatural amino acids cannot be obtained by fermentation or from natural sources, they must be prepared by conventional synthesis followed by racemate resolution, by asymmetric synthesis, or by biotransformation of chiral or prochiral precursors. Thus, amino acids represent an important class of compounds that can benefit from more efficient separations technology. 

A major theme running through these chapters is the added complexity inherent in the biosynthesis of macromolecules that contain information. Assembling nucleic acids and proteins with particular sequences of nucleotides and amino acids represents nothing less than preserving the faithful expression of the template... 

The genetic code is highly degenerate, with most amino acids represented by more than one codon. In many cases the 3 base in the codon may be altered without changing the amino acid that is encoded. 

Evolving proteins in general may of course change some of their amino acids but only at sites which are not crucial for the maintenance of their particular functions. Thus, the MM which is largely composed of acidic amino acids represents a... 

Most typical umami substances are divided into two series of compounds. One is a group of L-a-amino acids represented by monosodium glutamate (MSG) (Table I) (10-15), and another is that including 5 -ribonucleotides and their derivatives, represented by disodium 5 -inosinate (IMP) or disodium 5 -guanylate (GMP)(Table II) (16. 17. 18. 19). The latter group of substances have only very... 

Try drawing some of the amino acids represented on p. 20 in a similar way, using the three guidelines. The bond angles at tetrahedral carbon atoms are about 109°. Make them look about 109° projected on to a plane (120° is a good compromise, and it makes the drawings look neat.)... 

Amino acids can form peptides with the elimination of H20 as follows (with amino acids represented as NH3+— X— GOO-) ... 

Anhydrides of A-carboxy-a-amino acids represent a separate class of monomers. They were discovered at the beginning of this century [57] (Leuchs anhydrides) and are of the general formula... 

The feasibility of on-bead screening of an SP tweezer library with soluble tripeptides was then evaluated. An 125-member SPpool library L36 was prepared (Fig. 9.51) from the key resin-bound intermediate 9.137 using mix-and-split protocols, three monomer sets M1-M3, each containing five a-amino acid representatives, and the... 

Peptide linkage the bond resulting from the condensation reaction between amino acids represented by... 

Side chain (of amino add) the hydrocarbon group on an amino acid represented by H, CH3, or a more complex substituent. (22.6)... 

Name the amino acids represented by each of the following abbreviations. (24.1)... 

---