Amino acid enantiomers energy values

Steric hindrance cannot be directly calculated, but a lower MI energy value indicates lower steric hindrance in a complex. This phenomenon ean be observed in enantiomer recognition and protein-ligand interactions, with the latter also being known as affinity. Such phenomena can be studied via amino acid enantiomer complexes. The optimized energy values of (I )- and (S)-alanine are the same, as summarized in Table 2.4. 

The calculated energy values of the amino acid enantiomers derivatized with (+)-l-(9-fluorenyl)ethyl chloroformate using the MM2 program are listed Tables 8.12 and 8.13 with chromatographic data measured in reversed-phase from ref. 18. The energy values of individual complexes between the model phase and an enantiomer are listed Table 8.13. 

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