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Amines SANPAH

SANPAH (N-succinimidyl-6-(4 -azido-2 -nitrophenylamino)hexanoate) is a heterobifunctional crosslinking agent containing an NHS ester and a photoreactive phenyl azide group (Thermo Fisher). The NHS ester end can react with amine groups in proteins and other molecules, forming... [Pg.310]

Figure 5.21 The reaction sequence of crosslinking with sulfo-SANPAH involves first derivatizing an amine-containing molecule using its NHS ester end to create an amide bond. Exposure to UV light then causes ring expansion to the dehydroazepine derivative, which can couple with amines to form the final conjugate. Figure 5.21 The reaction sequence of crosslinking with sulfo-SANPAH involves first derivatizing an amine-containing molecule using its NHS ester end to create an amide bond. Exposure to UV light then causes ring expansion to the dehydroazepine derivative, which can couple with amines to form the final conjugate.
Figure 28.8 The heterobifunctional crosslinkers sulfo-SAND, SANPAH, and sulfo-SANPAH contain an amine-reactive (sulfo)NHS ester on one end and a photoreactive phenyl azide group on the other end. Sulfo-SAND allows release of conjugates by reduction of its internal disulfide bridge. Figure 28.8 The heterobifunctional crosslinkers sulfo-SAND, SANPAH, and sulfo-SANPAH contain an amine-reactive (sulfo)NHS ester on one end and a photoreactive phenyl azide group on the other end. Sulfo-SAND allows release of conjugates by reduction of its internal disulfide bridge.
See other pages where Amines SANPAH is mentioned: [Pg.1016]    [Pg.281]    [Pg.284]    [Pg.261]    [Pg.264]   
See also in sourсe #XX -- [ Pg.310 ]

See also in sourсe #XX -- [ Pg.261 ]

See also in sourсe #XX -- [ Pg.261 ]



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