Ambulatory infusion pump

Drug is administered chronically on an ambulatory basis with a portable infusion pump through a permanent central venous cathether peripheral IV infusions may be used temporarily until central venous access obtained... 

Alaris Medical Systems http //www.alarismed.com Infusion pump systems, ambulatory pumps, needlefree systems, intravenous administration sets... 

Kim HC, Bae YH, Kim SW (1999) Innovative ambulatory drug delivery system using an electrolytic bydrogel infusion pump. IEEE Trans Biomed Eng 46 663-669... 

However, one disadvantage associated with the use of most recombinant molecules is their rapid clearance. Because of this rapid clearance, recombinant molecules require repeated administration to achieve biological efficacy. Initially, continuous infusion was used to address this pharmacological deficiency. Continuous infusion has the advantage of delivering drugs in a controlled manner and is particularly appropriate when it is important to maintain constant plasma drug concentrations. However, the requirement for continuous venous access and the use of ambulatory pumps limits its use. 

Hadfield, J.A. McGown, A.T. Dawson, M.J. Thatcher, N. Fox, B.W. The suitability of carboplatin solutions for 14-day continuous infusion by ambulatory pump an HPLC-dynamic FAB study. J.Pharm.Biomed.Anal., 1993, 11, 723-727... 

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