Aluminum complexes cyanates

Cyanations. Aluminum complexes with diarylphosphine oxide groups possev cyanation of aldehydes and imines- with in a manner analogous to the Reisser asymmetric Strecker synthesis is applic reactivity of Me SiCN than HCN in the p catalytic amount while supplying stoichica... 

Cyanadons. Aluminum complexes of BINOLs (1) that are armed at C-3 and C-3 with diarylphosphine oxide groups possess both Lewis acid and base centers. Asymmetric cyanation of aldehydes and mines with MeaSiCN, and of quinolines and isoquinolines in a manner analogous to the Reissert reaction is successful (ee 70-90%). The asymmetric Strecker synthesis is applicable to conjugated aldimines and the higher reactivity of Me SiCN than HCN in the presence of 10 mol% of PhOH enables its use in catalytic amount while supplying stoichiometric HCN as the cyanide source. 

Since the addition of HCN to carbonyl compounds proceeds in the presence of a catalytic base, asynunetric cyanation should also be possible by using metal alkoxides such as boron, aluminum, titanium, zirconium, and lanthanoids through modification with an optically active substituent or ligand. Mori and Inoue reported that the titanium complex of an acyclic dipeptide composed of... 

---