Aluminofluoride complexes

Since hydrogen ions are six to twelve times more mobile than other cations, there will be a delay between loss of hydrogen ions from solution and migration of glass cations into the aqueous phase. Presumably, this electrical imbalance results in an electric field which acts as a driving force for the migration of cations. Aluminium and fluoride are almost certainly transported as cationic aluminofluoride complexes, AIF and AIFJ, mentioned above. 

Strunecka A, Patocka J (2003) Aluminofluoride Complexes in the Etiology of Alzheimer s Disease 104 139-180... 

This approach may not account for all the fluoride released by glass-ionomers [252], A recent study has used two methods of decomplexation of fluoride, using the same solutions for both methods, by dividing a given storage volume into two and treating each aliquot differently. One aliquot was diluted with an equal volume of TISAB, as is usual in the determination of fluoride by ion-selective electrode. The other solution was treated with a small volume of 4 M hydrochloric acid, allowed to stand for 3 h, then neutralised with an equal amount of 4 M sodium hydroxide. A volume of TISAB equal to the initial volume of the aliquot was added. This technique is known to liberate fluoride from monofluorophosphate as well as from aluminofluoride complexes [253],... 

Keywords Alzheimer s disease, Aluminum, Fluoride, Aluminofluoride complexes, G-protein... 

The tremendous possibilities of potential molecular interactions of aluminum, fluoride and aluminofluoride complexes probably exist in the brain. However, it is evident that interventions of aluminofluoride complexes into the nerve regulations could have severe physiological and pathophysiological consequences. 

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