Alternating-Current Electrode Polarization in Microelectrode Systems

Alternating-Current Electrode Polarization in Microelectrode Systems 

One can write a Laplace transform system transfer function for the circuit model. This is (neglecting the resistor shunting Q) 

Theoretically, it is now possible to calculate the inverse problem. Experimentally, V t) can be determined as this is the recorded signal, usually an action potential. With some effort, VXt) can be specified as a function of time and its Laplace transform computed. The Laplace transform f (s) of the input signal (action potential, etc.) l (t) is computed from the relations 

These relations hold provided that Cp, C,-, Rg, R, and Rp are known. Herein lies the difficulty. C(, Rg, and Rj are system parameters which are easily determined, but Cp and Rp are functions of frequency, hence functions of the 

Thus although theoretical calculations are possible, they are not practical, as there are undetermined and difficult-to-determine system parameters. For this reason, we turn now to a purely experimental approach. 

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Alternating-Current Electrode Polarization in Microelectrode Systems 73... 

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