Almotriptan drug interactions

ALMOTRIPTAN, ELETRIPTAN CARBAMAZEPINE Possible 1 plasma concentrations of almotriptan and risk of inadequate therapeutic efficacy. Risk of serotonin syndrome One of the major metabolizing enzymes of almotriptan - CYP3A4 isoenzymes - is induced by rifampicin. As there are alternative metabolic pathways, the effect may not be significant and can vary from individual to individual. Triptans and carbamazepine are both stimulants of 5-HT receptors, and carbamazepine in addition prevents the reuptake of 5-HT Be aware of possibility of l response to triptan, and consider T dose if considered to be due to interaction. Be aware of the possibility of the occurrence of serotonin syndrome >- For signs and symptoms of serotonin toxicity, see Clinical Features of Some Adverse Drug Interactions, Serotonin toxicity and serotonin syndrome... 

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