Allylations and Aldol-Type Reactions

The reactions of this section use stabilized carbanions formed from C—H-addic compounds by deprotonation. As phosphines are the only successful ligands known up to now, these reactions have been discussed in detail in Chapter 2, and we will again restrict this section to a few highlights. Carbanions derived from 1,3-diketones react with allylic esters enantioselectively under palladium catalysis with more than 80% ee [175]. Benzylamine is allylated by the same catalytic system, leading to substituted allyl-benzylamines with up to 97% ee (Fig. 4-32c) [176]. 

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