Alkyne-allenylcyclobutanes

Rh(I)-catalysed intramolecular 6 -I- 2-cycloaddition of alkyne-allenylcyclobutanes has been reported for the preparation of bicyclo[6.4.0]dodecatrienes (Scheme 155). ... 

Inagaki, R, Sugikubo, K., Oura, Y, Mukai, C. (2011). Rh -catalyzed [6+2] cycloaddition of alkyne-allenylcyclobutanes a new entry for the synthesis of bicyclo[6.m.O skeletons]. Chemistry European Journal, 17, 9062-9065. 

Mukai and coworkers have developed an intramolecular rhodium(I)-catalyzed [6+2] cycloaddition between an a-allenylcyclobutane and an alkyne moiety. The reaction proceeded under mild conditions to form bicyclo[6.w.O] (m = 3, 4) frameworks in high yields. It is worth noting that these cycloadditions involve an a-vinylcyclobutane moiety as the six-carbon component (Scheme 8.28) [47]. 

Scheme 8.28 Rh(I)-catalyzed [6+2] cycloaddition of alkyne-tethered allenylcyclobutane.

---

See also in sourсe #XX -- [ ]

---