3-Alkylpiperidine alkaloids total synthesis

Chiral 3-alkylpiperidines were prepared through perhydropyrido[2,I-Z)][],3]benzoxazines (99TL242I, 00TA2809). 5u-Pentyl-5u,6,7,8,9,H-hexa-hydropyrido[2,I-Z ][l,3]benzoxazin-9-ones 31, 33 (R CsHn) and 34 were used in the total synthesis of racemic and natural (—)-(R) forms of adalinine alkaloid (99SL37, 99TL739). 

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