Alkamine degradation

XXX) by reduction to XXXII and subsequent acetobromolysis, and this product was converted into the ( —)-diol XXXI, identical with the alkamine of natural valeroidine (III). Inversely, partial methylation 39b) of that diol gave the methiodide (XXXIII) of (— )-6(8-methoxy-tropine so that no breaking of the C-6—0 bond occurred during demethy-lation hence, the methoxyl and hydroxyl groups are both The degradation by nitric acid of the (+ )-2,4-dioximino-3-tropanone (39 a,b) furnished 25% of [Pg.280]

The more common and more exhaustively investigated alkamines of the Solanum group on selenium dehydrogenation have yielded the typical steroid dehydrogenation product, namely 7-methylcyclopentenophen-anthrene. The nitrogen in these degradations appears in the form of... 

The most significant chemical progress in the last decade has been the isolation and structural elucidation of an increasing number of new steroidal alkamines and glycosides the structures of which, however, still belong to one of the known types 1-5. Extensive work has also been directed to a number of new partial and total syntheses as well as to the degradation of the alkamines, particularly to pregnane derivatives. A number of review articles have been published in the last years (e.g., 31-38). 

Additional Nitrogenous Stercmds Derived by Degradation or Synthesis of Solanum Alkamines... 

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