Aliphatic Nitrites

The molecular ion peak (odd number) of aliphatic nitrites (one N present) is weak or absent. The peak at m/z 30 (NO+) is always large and is often the base peak. There is a large peak at m/z 60 (CH2=ONO) in all nitrites unbranched at the a carbon this represents cleavage of the C—C bond next to the ONO group. An a branch can be identified by a peak at m/z 74, 88, or 102,. Absence of a large peak at m/z 46 permits differentiation from nitro compounds. Hydrocarbon peaks are prominent, and their distribution and intensities describe the arrangement of the carbon chain. 

---

Nitro compounds and aliphatic nitrites (should observe M -... 

The involvement of an intramolecular hydrogen abstraction in the Barton reaction is not necessarily limited to those molecules with rigid stereochemistry. In fact, simple aliphatic nitrites undergo the Barton reaction with equal ease. Thus, the principal product obtained from the photolysis of ra-octyl nitrite20 in benzene solution is the dimer of 4-nitroso-l-octanol however, photolysis of n-octyl nitrite in n-heptane20 produced a mixture of 7/-nitroso heptanes in addition to 4-nitroso-l-octanol in the ratio l 4.5,f respectively. The formation of y-nitroso heptane obviously results from an attack of the intermediate alkoxy radical on the solvent molecule. The intermediate alkyl radical then collapses, according to eq. 2. For the sake of convenience we have indi-... 

There are few studies or research data that tracks the scope and severity of amyl nitrite usage, particularly among adults. It is usually lumped in the general category of inhalants. However, it is generally believed the problem is not as severe as with other, more readily available inhalants, such as solvents, aerosol propellants, and aliphatic nitrites, such as cyclohexyl nitrite. 

Meyer synthesis. Formation of aliphatic nitrites and nitro derivatives by the reaction of aliphatic halides with metal nitrites. 

The aliphatic nitrites are readily soluble in the halogenated NMR solvents carbon tetrachloride and deuterochloroform. No special solvent effects have been noted. 

---