Alginate macromolecules

Eiselt, P., Lee, K. Y, and Mooney, D. J. 1999. Rigidity of two-component hydrogels prepared from alginate and polyfethylene glycolj-diamines. Macromolecules 32(17) 5561-5566. 

Lee KY, Rowley JA, Eiselt P, Moy EM, Bouhadir KH, and Mooney DJ. Controlling mechanical and swelling properties of alginate hydrogels independently hy cross-linker type and cross-linking density. Macromolecules 2000 33 4291 294. 

In the area of controlled release, the preparation of indomethacin sustained-release microparticles from alginic acid (alginate)-gelatin hydrocolloid coacervate systems has been investigated. In addition, as controlled-release systems for liposome-associated macromolecules, microspheres have been produced encapsulating liposomes coated with alginic... 

Edible films and coatings are thin materials made from biological macromolecules (biopolymers).1 The main biopolymers used in preparing biofilms are polysaccharides2 and proteins.3,4 Among the most studied polysaccharides are pectin, cellulose and derivatives, alginates, carrageenan, chitosan and starch.1 5... 

Peng P et al (2008) Concurrent elution of calcium phosphate and macromolecules from alginate/chitosan hydrogel coatings. Biointerphases 3(4) 105-116... 

Hosseini, S. M., Hosseini, H., Mohammadifar, M.A., Mortazavian, A. M., Mohammadi, A., Khosravi-Darani, K., Shojaee-Aliabadi, S., Dehghan, S., and Khaksar, R. (2013). Incorporation of essential oil in alginate microparticles by multiple emulsion/ionic gelation process. International Journal of Biological Macromolecules, 62, 582-588. 

Most studies on microbial exopolysaccharides production have been performed so far using batch fermentation conditions and polymer macromolecules are recovered from fermentation broths by simple chemical and physical techniques, e.g. precipitation and centrifugation. In Scheme 7.2 the route of production of alginate is presented [8]. Some attempts have been made to apply immobilized-cell cultures to the production of alginate and other bacterial polysaccharides. Immobilization techniques are likely to allow the permanent separation of microbial cells from the incubation broth. In the last few years, however, membrane processes have been increasingly used to separate microbial cells from the production medium. A number of studies have therefore focused on the microfiltration of fermentation broths after batch incubation and the mechanisms of membrane fouling by cells, debris, colloidal particles and macromolecules, e.g. for recovery of polysaccharides from fermentation broths [2]. 

Reprinted from P. Mukhopadhyay, S. Chakrahorty, S. Bhattacharya, R. Mishra, P.P. Kundu, pH-sensitive chitosan/alginate core-shell nanoparticles for efficient and safe oral insulin dehvery. International Journal of Biological Macromolecules 72 (2015) 640-648. Copyright (2015), with permission from Elsevier. 

S. Jana, A. Das, A.K. Nayak, K.K. Sen, S.K. Basu, Aceclofenac-loaded unsaturated esteri-fled alginate/geUan gum microspheres in vitro and in vivo assessment. International Journal of Biological Macromolecules 57 (2013a) 129-137. 

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