Macrolides Alfentanil

A4 Acetaminophen, alfentanil, amiodarone, astemizole, cocaine, cortisol, cyclosporine, dapsone, diazepam, dihydroergotamine, dihydropyridines, diltiazem, ethinyl estradiol, gestodene, indinavir, lidocaine, lovastatin, macrolides, methadone, miconazole, midazolam, mifepristone (RU 486), paclitaxel, progesterone, quinidine, rapamycin, ritonavir, saquinavir, spironolactone, sulfamethoxazole, sufentanil, tacrolimus, tamoxifen, terfenadine, testosterone, tetrahydro-cannabinol, triazolam, troleandomycin, verapamil Barbiturates, carbamazepine, macrolides, glucocorticoids, pioglitazone, phenytoin, rifampin Erythromycin, 613-hydroxy cortisol... 

OPIOIDS MACROLIDES Effects of alfentanil t by eiythromycin Erythromycin inhibits metabolism of alfentanil Be aware that the effects of alfentanil (especially when given as an infusion) may be prolonged by eiythromycin... 

The metabolism of alfentanil, a potent short-acting narcotic, is inhibited by macrolide antibiotics, resnlting in significant changes in half-life and clearance (86). 

---