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Hyaluronic acid-aldehyde

Ruhela, D., Riviere, K., Szoka, F. C. Efficient synthesis of an aldehyde functionalized hyaluronic acid and its appUcation in the preparation of hyaluronan-hpid conjugates. Bioconjugate Chem. 2006, v. 17. Iss. 5, 1360-1363. [Pg.29]

From the chemical point of view, hyaluronan possesses four different types of functional groups acetamide, carboxylic acid, hydroxyl and terminal aldehyde. After deacetylation, a free amine could be obtained from an acetamide group. All four functionalities permit characteristic chemical reactions. Such a wide variety of possible chemical modifications creates a sharp difference between hyaluronic acid and other polysaccharides whose reactivity depends mainly upon hydroxyl groups. [Pg.121]

In situ cross-linkable chitosan-hyaluronic acid based hydrogels for preventing postoperative adhesion has been developed [153]. Hyalmonic acid was oxidized with sodium periodate which cleaves carbon-carbon bonds to create aldehyde groups in D-glucuronic acid units of the molecular chain. The solubility of chitosan in neutral aqueous solution was improved by incorporating carboxymethyl... [Pg.247]

See other pages where Hyaluronic acid-aldehyde is mentioned: [Pg.36]    [Pg.114]    [Pg.115]    [Pg.165]    [Pg.36]    [Pg.114]    [Pg.115]    [Pg.165]    [Pg.260]    [Pg.609]    [Pg.110]    [Pg.133]    [Pg.632]    [Pg.14]    [Pg.121]    [Pg.124]    [Pg.311]    [Pg.15]    [Pg.922]    [Pg.129]    [Pg.576]    [Pg.654]    [Pg.224]    [Pg.154]    [Pg.154]   
See also in sourсe #XX -- [ Pg.165 ]



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