Albumin, bovine serum conformational transitions

White, D. D., Stewart, S. and Wood, G. C. 1973. The use of reporter group circular dichroism in the study of conformational transitions in bovine serum albumin. FEBS Lett. 33, 305-310. 

Hypersensitive transitions can be useful for the study of structure, conformation and binding modes of biomolecules, and of reaction mechanism of biochemical reactions involving calcium ions. Bimbaum et al. (1970, 1976, 1977) have used changes in the shape and intensity of the hypersensitive transition Gs/2 <— 19/2 of Nd + in absorption difference spectra as a spectral probe for exploring the binding of Nd with bovine trypsin and bovine serum albumin. The possibility of probing the binding characteristics of biomolecules via hypersensitive transitions has been reviewed by Misra and John (1993). 

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