Alanine alcohol dehydrogenase

Acylation reaction, 171 Alanine, structure of, 110 Alcohol dehydrogenase, 205 Amide hydrolysis, see also Serine proteases Trypsin... 

Adenosine 5 -(tr1hydrogen diphosphate), 5 5 ester with 3-(ami nocarbonyl)-alcohol dehydrogenase, 63, 17 Adogen 464 [50934-77-5], 60, 11 Alanine, L-, N-carboxybenzyl ester, 63, 182 ALANINE, PHENYL-, N-tert-BUTOXYCARBONYL-, L-, 63, 160 Alanine, N-[(phenylmethoxy)carbonylL- [1142-20-7], 63, 182 Alcohols, alkynyl-, synthesis of, 63, 61 Alcohols, amino-, by reduction of acids, 63, 138 Aldol condensation, intramolecular, asymmetric, 63, 26, 37 Aldol condensation, diastereoselectlve, 63, 94, 104 ALIPHATIC B-KETOESTERS, 61, 5 Alkene photodimerization, 62, 125... 

Bacterial membranes contain respiratory enzymes resembling those found in inner mitochondrial membrane (Haddock and Jones, 1977), which oxidize NADH to NAD+ and H20. C.freundi grown aerobically, possess a particularly active membrane-bound NADH-oxidase activity (1.0—1.5 pmol/min-mg of protein at 30°C. Since these membranes alone or in the presence of NAD+ do not oxidize substrates such as L-alanine, L-lactate, or ethanol, they act as indicators of the activity of lactate dehydrogenase, alanine dehydrogenase, or alcohol dehydrogenase ... 

Thus, if the amino acid (Figure 8.23) is alanine (R3 = -CH3), widely represented in must and wine, the corresponding aldehyde is ethanal. If the amino acid is methionine (R4 = CH3-S-CH2-CH2-), which is certainly only present in small quantities but is reputed to be highly reactive with carbonylated compounds, then methional, or -methyl-S-propanal, is produced. This compound is thermally unstable and evolves rapidly, via a Retro-Michael reaction, into acrolein and methanethiol (Figure 8.28). These smell of cooked cauliflower, wet dog, etc. In wine, part of the methional returns to methionol via catalyzed reduction by alcohol dehydrogenase with NADH. 

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