Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Al,4-GlcNAc

Heparosan [pl,4GlcA-al,4 GlcNAc] TypeD Type A,D,F PmHSI PmHS2... [Pg.265]

Several fucosyltransferases have been isolated and used for in vitro synthesis. The Lewis A al,4-fucosyltransferase transfers unnatural fucose derivatives in from their GDP esters [23]. The enzyme al,3-fiicosyltransferase has been used to L-fucosylate the 3-position of the GlcNAc of A-acetyllactosamine and of sialyl a2,3-N-acetyllactosamine [24]. Several acceptor substrates with modifications in the GlcNAc residue could also be... [Pg.490]

Polyphosphate kinase has been found able to phosphorylate nucleoside diphosphates to give nucleoside triphosphates, using PolyP as a phosphate donor. Therefore, the possibility of using PolyP and polyphosphate kinase instead of phosphoenol pyruvate and pyruvate kinase for enzymatic oligosaccharide synthesis was examined, because PolyP is quite cheap when compared with phosphoenol pyruvate (Noguchi and Shiba, 1998 Shiba et al, 2000). Attempts were made to synthesize N-acetyllactosamine (Gal (f> 1-4) GlcNAc) using the nucleoside diphosphate kinase-like activity of polyphosphate kinase, where UDP-Glc pyrophosphorylase and UDP-Glc 4-epimerase catalyse the synthesis of UDP-Glc from... [Pg.187]

Linked fucose has been found on the EGF domains of urokinase, tissue plasminogen activator (tPA), factor VII, and factor XII, attached to the consensus sequence Cys-Xaa-Xaa-Gly-Gly-Ser/Thr-Cys. The fucosyltransferase responsible for the initiation of this type of gly-cosylation has been cloned [165]. On human (but not bovine) factor IX the tetrasaccharide Neu5Ac(o 2-6)Gal(jSl—4)GlcNAc( 81-3)Fuc(al-0)Ser (O Fig. 13d) was found [166,167]. In other FGF domains only Fuc(a l-0)Ser/Thr was detected. [Pg.1757]

Man (al-6), Man (al-3) Man (Pl-4) GlcNAc (Pl-4) GlcNAc This core can be extended to form (1) a high mannose type, where several Man residues are attached to the core, (2) a complex type, where up to five antennae of Gal-GlcNAc and capped with sialic acids are attached to the core, or (3) a hybrid type with a combination of (al-6)-linked Man and (al-3)-linked complex antennae are attached to the core. [Pg.533]

See other pages where Al,4-GlcNAc is mentioned: [Pg.189]    [Pg.189]    [Pg.443]    [Pg.1375]    [Pg.2286]    [Pg.256]    [Pg.256]    [Pg.257]    [Pg.257]    [Pg.257]    [Pg.365]    [Pg.611]    [Pg.612]    [Pg.189]    [Pg.189]    [Pg.443]    [Pg.1375]    [Pg.2286]    [Pg.256]    [Pg.256]    [Pg.257]    [Pg.257]    [Pg.257]    [Pg.365]    [Pg.611]    [Pg.612]    [Pg.191]    [Pg.332]    [Pg.362]    [Pg.94]    [Pg.105]    [Pg.269]    [Pg.98]    [Pg.99]    [Pg.101]    [Pg.417]    [Pg.49]    [Pg.95]    [Pg.95]    [Pg.95]    [Pg.70]    [Pg.368]    [Pg.592]    [Pg.594]    [Pg.596]    [Pg.640]    [Pg.70]    [Pg.70]    [Pg.37]    [Pg.38]    [Pg.38]    [Pg.1375]    [Pg.1750]    [Pg.1752]    [Pg.1758]    [Pg.2258]    [Pg.2281]   
See also in sourсe #XX -- [ Pg.1375 ]



SEARCH



GlcNAc

© 2024 chempedia.info