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Agonist ligand binding

A ligand can be an antagonist or agonist that binds to a receptor. [Pg.690]

Receptors permanently linked to an effector consist of proteins with an extracellular ligand-binding receptor domain and a signal-generating effector domain (Fig. 1). Most of these receptors are composed of two to five structurally related or identical subunits. Effectors can be enzymes or ion channels whose activities are stimulated by agonist binding without significant delay. [Pg.1237]

In the monoamine receptors the ligand-binding domain is located within the transmembrane helices. A pocket is formed between TM3, TM5 and TM6 where the agonist binds. A conserved aspartate residue in TM3 (Asp-113 in the /(-adrenoceptor) and a... [Pg.70]

See other pages where Agonist ligand binding is mentioned: [Pg.517]    [Pg.588]    [Pg.78]    [Pg.170]    [Pg.465]    [Pg.31]    [Pg.102]    [Pg.156]    [Pg.517]    [Pg.588]    [Pg.78]    [Pg.170]    [Pg.465]    [Pg.31]    [Pg.102]    [Pg.156]    [Pg.48]    [Pg.656]    [Pg.98]    [Pg.108]    [Pg.219]    [Pg.275]    [Pg.276]    [Pg.205]    [Pg.205]    [Pg.206]    [Pg.223]    [Pg.357]    [Pg.13]    [Pg.16]    [Pg.69]    [Pg.69]    [Pg.71]    [Pg.87]    [Pg.118]    [Pg.160]    [Pg.46]    [Pg.90]    [Pg.422]    [Pg.547]    [Pg.554]    [Pg.795]    [Pg.797]    [Pg.891]    [Pg.894]    [Pg.1018]    [Pg.1071]    [Pg.1114]    [Pg.1188]    [Pg.123]    [Pg.389]    [Pg.183]    [Pg.329]    [Pg.73]    [Pg.144]   
See also in sourсe #XX -- [ Pg.75 , Pg.76 ]



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Agonist binding

Ligand affinity agonist-receptor binding, dissociation

Ligands agonists

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