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Agitation Intensity—Low Deformability Growth

Three regimes of granule growth may be identified for low-agitation intensity-low-deformability processes (3,43), as depicted for fluid-bed granulation in Figure 39, and outlined as follows ... [Pg.46]

Types of Granule Growth The importance of deformability to the growth process depends on hed agitation intensity. If little deformation takes place during granule collisions, the system is referred to as a low-deformahility or low-agitation-intensity... [Pg.2332]

Rate of growth (high deformability) Decrease binder viscosity. Increase agitation intensity. Increase particle density. Increase rate of nuclei formation, collision frequency, and residence time, as above for low-deformability systems. Decrease binder concentration or change binder. Decrease any diluents and polymers that act as thickeners. Decrease operating temperature for systems with simultaneous drying. (Otherwise increase temperature. Increase mixer impeller or drum rotation speed or fluid-bed gas velocity. [Pg.2358]

See other pages where Agitation Intensity—Low Deformability Growth is mentioned: [Pg.2245]    [Pg.2337]    [Pg.2228]    [Pg.2320]    [Pg.95]    [Pg.2245]    [Pg.2337]    [Pg.2228]    [Pg.2320]    [Pg.95]    [Pg.2337]    [Pg.2320]    [Pg.95]    [Pg.1882]    [Pg.1882]    [Pg.1883]    [Pg.1641]    [Pg.1641]    [Pg.1642]    [Pg.2333]    [Pg.2359]    [Pg.2316]    [Pg.2342]    [Pg.1886]    [Pg.1886]    [Pg.1887]    [Pg.91]    [Pg.117]    [Pg.37]    [Pg.37]   


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Low-intensity

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