Aggregate dose, defined

Our results for HOC partitioning in the presence of sorbed surfactant and micelles demonstrate that large differences can exist in the HOC sorption capacity of surfactant aggregates in micellar versus sorbed forms. This can be seen quite readily by calculating Kss values as a function of surfactant dose from the experimental KD values. The distribution coefficient defines the HOC mass balance and can be expressed as ... 

ED50 values are determined from the dose-response curves. ED50 is defined as the dose of drug leading to 50 % inhibition of aggregation in the animals. 

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