Agents of Respectability

In exposures by inhalation of airborne materials, the dose is the concentration multiplied by the time (CT), and is roughly a constant for any given material and specified effect. The CT value can be used to provide a rough approximation of other combinations of concentration and time which would have about the same effect. Although this concept must be used very cautiously and cannot be applied at extreme conditions of either concentration or time, it is most important in setting limits for airborne contaminants and physical agents in respect to environmental exposures. The worker is exposed for various periods of time, day after day, to the... 

Alkenes are especially good alkylating agents. With respect to them the reaction is addition of ArH to a C=C double bond ... 

Mycobacteria consist of a fairly diverse group of acid-fast bacteria. The best-known members areM tuberculosis andM leprae, the causative agents of tuberculosis and leprosy, respectively. Other mycobacteria can also cause serious irrfection, e.g. members of the MAI group, and there are many opportunistic species. 

Metal coordination is another important bonding opportunity with respect to self-assembly. This is important in many natural molecules such as hemoglobin and chlorophyll, where the metal atom acts both as the site of activity and as a centralizing agent with respect to shape and thus acts as a nucleating agent for self-assembly. 

Benzylpenicillin or penicillin G has a narrow antimicrobial spectrum. It is active with respect to Gram-positive bacteria (staphylococcus, streptococcus, and pneumococci), causative agent of diphtheria, and anthrax bacillus. Gram-negative bacteria are resistant to it. Benzylpenicillin is broken down by stomach acid and destroyed by staphylococcus penicillinase. 

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