Advances in Asymmetric Hydroboration

In this chapter, recent advances in asymmetric hydrosilylations promoted by chiral transition-metal catalysts will be reviewed, which attained spectacular increase in enantioselectivity in the 1990s [1], After our previous review in the original Catalytic Asymmetric Synthesis, which covered literature through the end of 1992 [2], various chiral Pn, Nn, and P-N type ligands have been developed extensively with great successes. In addition to common rhodium and palladium catalysts, other new chiral transition-metal catalysts, including Ti and Ru complexes, have emerged. This chapter also discusses catalytic hydrometallation reactions other than hydrosily-lation such as hydroboration and hydroalumination. 

K. Burgess and W. A. van der Donk, Asymmetric Hydroboration, in Advanced Asymmetric Synthesis , ed. 

Methyl L-ohvoside (24) is an important compound, because it has been repeatedly used as a key intermediate for synthesis of other deoxypyrano-sides, e.g., L-oleandroside, L-kedarosaminide, L-ristosaminide, and L-daunos-aminide [20]. The examples of its syntheses presented above could be easily multiplied by application of known principles of acychc stereoselection, e.g., asymmetric hydroboration, epoxidation, dihydroxylation, etc. Considering recent advances in enantioselective synthesis based on asymmetric... 

Crudden, C. M. Edwards, D. Catalytic Asymmetric Hydroboration Recent Advances and Applications in Carbon-Carbon Bond-Forming Reactions. Eur. J. Org. Chem. 2003,2003,4695 12. 

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