Addition of terminal alkynes to activated

On the other hand, Chen and Li reported a facile and selective copper-palladium-catalyzed addition of terminal alkynes to activated alkynes in water without the competition of the homocoupling of the terminal alkynes (Eq. 4.79). Subsequently, a simple and highly efficient Pd-catalyzed addition of a terminal alkyne to a C—C double bond, such as a conjugated enone, either in water or in acetone, was also developed (Eq. 4.80). A variety of... 

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