Decarboxylative fluorination acyl hypofluorites

A new fluorinating reagent (F-TEDA-BF ) was found to react with pyrrole-2-carboxylates to give 2-fluoropyrroles. <95CC2399> The mechanism has not been established but might involve decarboxylation of an acyl hypofluorite. 

Decarboxylative fluorination, presumably via intermediate acyl hypofluorites, has been achieved in low yield by passing a dilute stream of fluorine in nitrogen into aqueous solutions of sodium carboxy-lates. A somewhat more promising method, tolerant of aryl groups, ketones and ethers, involves reaction of a dichloromethane solution of the acid with xenon difluoride and hydrogen fluoride (equation 23). 7... 

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See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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