Acyclic Systems Crams Rule, Felkin-Ahn Model

DIASTEREOSELECTIVITY IN ACYCLIC SYSTEMS CRAM S RULE, FELKIN-AHN MODEL 

In an acyclic system, rotations about carbon-carbon bonds can alleviate steric strain. While the existence of many possible conformations makes it more 

Introduction to Strategies for Organic Synthesis, First Edition. Laurie S. Starkey. 2012 John Wiley Sons, Inc. Published 2012 by John Wiley Sons, Inc. 

L = Largest group M = Medium-sized group S = Smallest group 

Electron-withdrawing group Larger group Smaller group EWGat90 for favored orientation major product 

---