Acyclic amidopyrrole

CYCLIC AND ACYCLIC AMIDOPYRROLE CONTAINING ANION RECEPTORS... 

While interesting neutral alternatives to the unsaturated expanded porphyrin derivatives, calix[n] pyrroles (n = 4, 5, 6, 8) are relatively limited in their scope for anion binding because of the constraints of the cavity size. Nevertheless pyrroles linked by an sp3 hybridised carbon atom are of considerable interest because of their resemblance to the anti-cancer agents the prodigiosins (Section 4.2.4), moreover pyrrole anion-receptor chemistry is synthetically versatile and hence a range of acyclic pyrroles and hybrid amidopyrroles such as 4.50-4.52 have been developed, particularly by the groups of... 

A range of acyclic pyrroles and hybrid amidopyrroles have been prepared. Sessler and co-workers investigated the propensity of linear bipyrroles 79a and 79b and tripyrroles 79c-e to complex and transport chloride [143]. The crystal structures of the complexes of 79a and 79c with CF were also obtained (Fig. 5.54). 

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