Acid dissociation constants of amino acids

At low pH, both the ammonium group and the carboxyl group are protonated. At high pH, neither is protonated. Acid dissociation constants of amino acids are listed in Table 10-1, where each compound is drawn in its fully protonated form. 

Table 10-1 Acid dissociation constants of amino acids... 

As in Section 14.3.3, we shall deal only with the rapid equilibrium of substrate and hydrogen-ion binding, because the full steady-state equations are very complex. Hence, the Michaelis constant represents the true dissociation constant of respective enzyme-substrate complexes, and Kp and Kb represent the acid dissociation constants of amino acids in the free and the bound enzyme, respectively. 

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See also in sourсe #XX -- [ , ]

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