Acetyl chloride hexahydro derivative

EUP161917,85EUP164247 91JMC19). l,3,4,6,7,116-Hexahydro[l,4]ox-azino[3,4-a]isoquinoline and its 4-oxo derivative were obtained by cycliza-tion of 3-[o-(2-chloroethyl)phenyl]morpholine and l-[(2-chloroethoxy)-methyl]-l,2,3,4-tetrahydroisoquinoline on the action of ferf-BuOK, and by cyclization of 2-[o-(3-morpholinyl)phenyl]acetyl chloride on the action of NEt3 (67BRP1094470,67NEP6611733). 

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