2-acetamido acetophenone

The Camps quinoline synthesis entails the base catalyzed intramolecular condensation of a 2-acetamido acetophenone (1) to a 2-(and possibly 3)-substituted-quinolin-4-ol (2), a 4-(and possibly 3)-substituted-quinolin-2-ol (3), or a mixture. 

ACETOPHENONE, 2-(2-ACETAMIDO-ETHYL)-4,5-DIMETHOXY- [ACETAMIDE, Ar-[2-(2-ACETYL-4,5 -DI-METHOXYPHENYL)ETHYL] -), 3 Acetophenone, 2-(2-acetamidoethyl)-4,5,6-trimethoxy- [Acetamide, A,-[2-(2-acetyl-3,4,5-trimcthoxyphenyl)ethyl ] -1,7... 

Acetonitrile, phenyl-, 55,91, 94 Acetonitrile-18-crown-6 complex, 57, 31 Acetophenone, 58, 57, 61 ACETOPHENONE, 2-(2-ACETAMIDO-ETHYLE4,5-DIMETHOXY-, 56, 3 Acetophenone, 2-(2-acetamidoethyl)-4,5, 6-trimethoxy-, 56, 7 Acetophenone, 4-chloro, 55, 40 Acetophenone, 4-chloro-, oxime, 55, 39, 40 7-Acetoxy-4,4,6,7-tetramethylbicyclo-[4 2 0] octan-2-one, 57, 113 Acctylacetone, 58, 52, 56 Acetyl chloride, a rert-butyl-o-cyano-, 55, 38... 

Acetamido ketones have been prepared in a multicomponent reaction from aromatic aldehydes, enolizable ketones (acetophenone and propiophenone), and acetyl chloride in acetonitrile over Nafion-H1002 [Eq. (5.363)]. High yields are achieved under mild conditions and the catalyst proved to be recyclable. 

COCH3 - Preparation by hydrolysis of 4-acetamido-2-hy-droxy-acetophenone with boiling aqueous hydro-NH2 chloric acid at 50% HCl [2468] or at 15% HCl... 

Preparation by hydrolysis of 5-acetamido-2-hydroxy-NH2 acetophenone with boiling aqueous hydrochloric acid... 

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