Aceon - Perindopril erbumine

Perindopril (aceon) Perindopril erbumine is a prodrug, and 30-50% of systemically available perindopiil is transformed to perindoprilat by hepatic esterases. The oral bioavailability of perindopril (75%) is not affected by food. Perindopril is metabolized to perindoprilat and to inactive metabolites (glucuronides of perindopril and perindoprilat, dehydrated perindopril, and diastere-omers of dehydrated perindoprilat) that are excreted predominantly by the kidneys. Peak concentrations of perindoprilat in plasma are achieved in 3-7 hours. Perindoprilat displays biphasic... 

Perindopril Erbumine (Aceon) [Antihypertensive/ACEI] Uses ... 

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