Accordion-optimized methods

The available accordion-optimized long-range heteronuclear shift correlation experiments were surveyed in a recent chapter. No novel accordion-optimized methods have been reported, but following the author s initial report on the advantages of using the IMPEACH-MBC sequence for long-range studies, Kline and Cheatham have... 

Accordion-optimized direct heteronuclear shift correlation methods 40... 

In 2001, Meissner and Sprensen described methods for the measurement of Jhh anO "Jch couplings employing the broadband excitation approach (see Section 3.3.7) with the report of the broadband XLOC and broadband J-HMBC experiments, respectively. In a further extension of the idea of accordion optimization, Williamson ef reported the development of the J-IMPEACH-MBC pulse sequence. This approach is similar to the EXSIDE experiment previously described by Krishnamurthy and the J-resolved HMBC experiments of Furihata and Seto"- in its use of J-scaling to render small, long-range heteronuclear couplings conveniently measurable. Finally, Williamson e/ also described a new method, G-BIRDr-HSQMBC, that was reported in their survey of the available methods. 

Accordion-optimized Long-range Heteronuclear Shift Correlation Methods. 

The idea of accordion-optimization is by no means new [143]. The idea of applying this method to the optimization of the long-range delay of HMBC-type experiments, however, was only reported in 1998 by Wagner and Berger [144] in their description of the ACGORD-HMBC experiment. The ACCORD-HMBG pulse... 

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