Access to the Proteolytic Chamber

ATPase. The corresponding translocation process catalyzed by PAN follows ATP-dependent unfolding (Navon and Goldberg 2001 Benaroudj et al. 2003). However, it still remains to be clarified whether complex formation is a prerequisite for the cooperation between PAN and CP or whether the two systems work independently. 

This notion was further confirmed by the crystal structure of a 20S/11S heterologous complex between the yeast 20S-proteasome and the Trypanosoma IIS-regulator (Whitby et al. 2000). This approach was justified by the ability of IIS reg- 

The Tricorn Protease and its Structural and Functional Relationship with Dipeptidyl Peptidase IV 

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