Acalypha indica Acalyphine

Acalypha indica L. China Acalyphine.55 Diuretic, treat diarrhea. 

The cyanogenic glucoside, acalyphin (Fig. 3.1), found in Acalypha indica, appears to be derived from nicotinic acid metabolism (Nahrstedt et al, 1982). Acalyphin is homologous to four non-cyanogenic 3-cyanopyridones, including ricinine, that have also been isolated from various Acalypheae (Nahrstedt, 1987). 

Acalyphin (84) is obtained from the weed Acalypha indica (A. Narstedt, J.-D. Kant and V. Wray, Phytochem., 1982, 21, 101) whereas another 2-pyridinone, campedine (85), has been isolated from Campanula medium (W. Dopke and G. Fritsch, Pharmazie, 1970, 25, 128). It should be noted however that W-ethyl groups are most uncommon in nature, and the possibility that this compoud is an artefact is very likely. 

A cyanogenic compound, acalyphin (51), that appears to have a similar biosynthetic origin has been isolated from Acalypha indica (Nahrstedt et al., 1982). 

Acalypha indica Euphorbiaceae Whole plant Acalyphine Citarasu et al. (1999)... 

Acalypha famesiana Willd. A. indica L. Jin He Huan Indian Ren Xian (Wild copper leaf) (whole plant) Acalyphine.55 Diuretic, treat diarrhea. 

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