A Virion-Associated Inhibitor

Experiments in which expression of viral genes was prevented have supported the proposition that a virion component can, in some 

The action of a herpes virion-associated inhibitor probably also explains the result of mixed infection with vesicular stomatitis virus (VSV Nishioka et ai, 1983). VSV alone shuts off cellular protein synthesis but less rapidly than HSV and without causing the disaggregation of polysomes. In mixed infection, VSV was dominant in that it prevented the production of HSV-specific proteins, apparently by inhibiting transcription, but the polysomes were dissociated and host protein synthesis ceased. 

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