A The amide, imide, and lactam configurations

In addition to several amides (asparagine, glntamine, urea), Doull et al. lists the imide 3,7-dihydro-l,3,7-trimethyl-l//-purine-2,6-dione (caffeine) among individual compounds used in cigarette manufacture by U.S. companies (1053). 

The seventy-nine imides identified in tobacco and tobacco smoke are cataloged in Table XIV-1. Of the seventy-nine imides reported, thirty-nine have been identified in tobacco, fifty-nine in tobacco smoke, and nineteen in both tobacco and smoke. 

FIGURE XIV-1 B The amide II, imide III, and lactam IV configurations in l-acetyl-3-ethyl-l,5-dihydro-4-methyl-2/f-pyrrol-2-one I.  

Imides Identified in Tobacco, Tobacco Smoke, and Tobacco Substitute Smoke 

CAS No. Name (per CA Collective Index) Tobacco smoke Tobacco Tobacco substitute smoke 

---