A-Selective thermal glycosidation

Nishizawa, M, Kan, Y, Shimomoto, W, Yamada, H, a-Selective thermal glycosidation of rhamnosyl and mannosyl chlorides, Tetrahedron Lett., 31, 2431-2434, 1990. 

HSDSC has also been used to study nucleotides that contain abasic sites (39). An abasic site (usually abbreviated to AP) is produced when a heterocyclic base is removed by the selective hydrolysis of an N-glycosidic bond. Abasic sites can form under physiological conditions — as the first step in DNA repair, for example — and are believed to play a significant role in mutagenesis. Using HSDSC, the thermal behavior of a series of DNA duplexes, shown later, was investigated. 

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