A New Three-component Process

A major advantage of this MCR is that organoboronic acids are readily available in a large variety of structural configurations and they can be formed in isomeri-cally pure forms. As a result of their widespread utility in Suzuki-Miyaura coupling [27, 28] and other reactions [29, 30], a variety of aryl and heteroaryl [31] boronic adds are now commercially available and can be employed in this MCR process. Most of these compounds are also air and water stable as well as non-toxic and environmentally friendly. They also tolerate many functional groups, thereby 

As summarized below, this method can be used for the facile synthesis of a variety of amine derivatives, including many potentially bioactive and drug-like molecules. Also, the multicomponent nature of this process and the availability of a wide range of components allows the facile synthesis of large combinatorial libraries of diverse molecules [32, 33]. 

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