A-Aryloxyisobutyric acids

Fibric acid derivatives (aryloxyisobutyric acids) include the prototypic drug gemfibrozil. These types of drugs are used mainly to lower triglycerides and to increase HDL. A large placebo-controlled primary prevention trial in hypercholesterolemic men showed that patients treated with gemfibrozil had a statistically lower number of myocardial infarctions, but not of deaths from all causes. 

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