A-Aminonitriles compounds

Fetterley et al. have been very active in determining the utility of strongly basic PAPT-type reagents in organic synthesis, and have reported that a-aminonitrile compounds could be efficiently synthesized by the Strecker condensation of aldehydes, amines, and trimethylsilyl cyanide (TMSCN) in the presence of a nitrate salt of PS-PAPT as a catalyst [34] (Scheme 6.5). In this work, the reusability of the catalyst was also established, and the catalyst activity was ascribed to the participation of a nitrate ion of the catalyst acted as a proton shuttle. ... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ , ]

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