Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

A Acetyldigoxin

C4()H7,jOi9 17575-20-1) see Acetyldigitoxin a-Acetyldigoxin Lanatoside C D-glucuronic acid... [Pg.2390]

C2HjNa02, 127-09-3) see a-Acetyldigoxin Dextrothyroxine Fluazacort Fluprednidene acetate Pioglitazone Pyrrocaine sodium acetoacetic acid ethyl ester (C HyNaO, 19232-39-4) see Pentoxifylline sodium acetylide (Na(C2H))... [Pg.2441]

Reisch, J., Zappel, J., and Rao, R.R. (1994) Photostability studies of ouabain, a-acetyldigoxin and digoxin in solid state, Pharm. Acta Helv., 69, 47-50. [Pg.388]

The filtrate, which results from the separation of product 1, is evaparated to dryness in vacuum. The residue, which mainly contains unreacted digoxin, is purified by recrystallization from pyridine/ether/water (3.5 5 40) and repeatedly acetylated. It can then be recycled to produce more p-acetyldigoxin. The filtrate resulting from the separation of product 2 is evaporated to dryness. The resulting residue contains the di- and polyacetyl derivatives of digoxin, which are deacetylated to digoxin in a known manner... [Pg.65]

Beta-Acetyldigoxin may be prepared from digoxin, acetic acid and dicyclohexylcarbodiimide using the last one as a condensing agent. [Pg.66]

Reisch J, Zappel J, Raghu A, Rao R. Photostability studies of ouabain, (-acetyldigoxin and digoxin in the solid state. Pharm Acta Helv 1994 69 47-50. [Pg.36]

A study in 6 healthy subjects given beta-acetyldigoxin 400 micrograms daily found that the half-life of digoxin was reduced by 30% (from 33.9 to 23.7 hours) and the AUC was reduced by 23% after they took phenytoin 200 mg twice daily for a week. Total digoxin clearance increased by 27% (from 258.6 to 32 3 mL/minute). ... [Pg.909]

Other studies confirm that a 50% reduction in serum digoxin levels (using beta-acetyldigoxin) occurred in patients given cyclophosphamide, vincristine, procarbazine and prednisone (COPP) cyclophosphamide, vincristine and prednisone (COP) cyclophosphamide, vincristine, cy-tarabine and prednisone (COAP) and doxorubicin, bleomycin and prednisone (ABP). These effects disappeared about a week after cytotoxic therapy finished. Radiation has a smaller effect. Digitoxin absorption does not seem to be affected by antineoplastics. ... [Pg.910]


See other pages where A Acetyldigoxin is mentioned: [Pg.24]    [Pg.24]    [Pg.24]    [Pg.25]    [Pg.2283]    [Pg.2284]    [Pg.2284]    [Pg.2353]    [Pg.2390]    [Pg.24]    [Pg.24]    [Pg.24]    [Pg.25]    [Pg.25]    [Pg.2353]    [Pg.2389]    [Pg.2390]    [Pg.185]    [Pg.402]    [Pg.24]    [Pg.24]    [Pg.24]    [Pg.25]    [Pg.2283]    [Pg.2284]    [Pg.2284]    [Pg.2353]    [Pg.2390]    [Pg.24]    [Pg.24]    [Pg.24]    [Pg.25]    [Pg.25]    [Pg.2353]    [Pg.2389]    [Pg.2390]    [Pg.185]    [Pg.402]    [Pg.27]    [Pg.27]    [Pg.99]    [Pg.834]    [Pg.132]    [Pg.249]    [Pg.356]    [Pg.66]    [Pg.26]    [Pg.27]    [Pg.27]    [Pg.333]    [Pg.651]    [Pg.656]    [Pg.136]    [Pg.306]    [Pg.490]    [Pg.495]    [Pg.106]    [Pg.903]   
See also in sourсe #XX -- [ Pg.402 ]




SEARCH



© 2024 chempedia.info