67Ga citrate

Kurosaki H, Saito Y, Kawashima M, Ebara T, Yamakawa M, Mitsuhashi N. Accumulation of 67Ga citrate in early pregnancy. Ann Nucl Med 2001 15(3) 289-91. 

The similarities of phthalocyanines and porphyrins have led to the screening of "mTc-and 67Ga-tetrasulphophthalocyanines for ability to detect tumours286. Whereas tumour blood and tumour muscle ratios for the Tc-chelate did not reach satisfactory levels within 24 h, satisfactory levels were reached for the Ga-chelate. Although the absolute level of tumour uptake to the Ga-chelate was 5-6 times lower than the absolute uptake of Ga-citrate, rapid blood clearance of the tetrasulphophthalocyaninate permitted an easier identification of tumours. The success of this work will no doubt lead to yet more developments in NIDM. The development of contrast agents based upon porphyrins and tetrasulphophthalocyanines is anticipated. 

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