Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

131I-tositumomab

Radioimmunotherapy is generally well tolerated. Toxicities include infusion-related reactions, myelosuppression, and possibly myelodysplastic syndrome or AML. 131I-tositumomab can cause thyroid dysfunction. [Pg.723]

Tositumomab is another anti-CD20 monoclonal antibody and is complexed with iodine 131 (131I). Tositumomab is used in two-step therapy in patients with CD20-positive, follicular non-Hodgkin s lymphoma whose disease is refractory to rituximab and standard chemotherapy. Toxicities are similar to those for ibritumomab and include severe cytopenias such as thrombocytopenia and neutropenia. Tositumomab should not be administered to patients with greater than 25% bone marrow involvement. [Pg.1198]

Kaminski MS, Tuck M, Estes J, Kolstad A, et al. 2005. 131I-Tositumomab therapy as initial treatment for follicular lymphoma. NEJM. 352 441-449. [Pg.124]

Bexxar Tositumomab Murine igCU CD20 B-cell NHL IV 450 mg tositumomab and 131I-tositumomab by dosimetry 1 Dose (65-75 cGy)... [Pg.313]

See other pages where 131I-tositumomab is mentioned: [Pg.723]    [Pg.69]    [Pg.723]    [Pg.69]    [Pg.393]    [Pg.194]    [Pg.367]   
See also in sourсe #XX -- [ Pg.902 , Pg.903 , Pg.905 ]



SEARCH



© 2024 chempedia.info