SEARCH Articles Figures Tables Validity check of substructure-based calculation approaches. [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint] [Publishers Imprint]