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CYP2B1-inactivation by BITC. The pathway proposed for the metabolism of BITC by CYP2B1 leads to the formation of a protein adduct. The circled area indicates the site of metabolism

CYP2D6 genotype dependent quantitative changes in pharmacokinetics of antidepressant drugs expressed as percent dose adaptations. CYP2D6 PM . Dose adaptations were calculated as described in . Dose adaptations are based on an average dose of 100 and are aimed for the Caucasian population. Data from studies in Asiatic or African or other populations were not incorporated because PM data are lacking. From Kirchheiner J, Nickchen K, Bauer M, et al. Pharmacogenetics of antidepressants and antipsychotics

CYP2D6 with Debrisoquine docked into a substrate recognition site showing interactions with

CYP2E1-catalyzed metabolism of fluorinated volatile anesthetics to antigenic proteins.

CYP2E1-mediated transformation of trichloroethylene TCE

CYP3A and CYP2B1 mRNA levels increased within two hours, reaching a maximum at 24 hours. Corresponding CYP protein induction requires at least eight hours before a significant rise is observed.

CYP3A potency indices of DFP in cultured rat hepatocytes as determined by Western blots, testosterone 6 3-hydroxylation, and DFP turnover. Abbreviation

CYP3A4 active site showing the predominantly hydrophobic cavity with a cluster of phenylalanines at the top. Arg212 is oriented into the cavity in this structure.

Cyp450 metabolism of miconazole.

CYP450-catalyzed reduction of azo and nitro compounds.

CYP88A catalyzes the three oxidative transformations required to convert ent-kaurenoic acid into GAj.

CYPllAl-catalyzed conversion of ergosta-5-ene-ol and ergosta-5,22-diene-ol to pregnenolone in recombinant yeast- CYPllAl reaction details described in Section 5.2.1 and

Cyprinol sulfate.

Cyproheptadine .

Cyproterone inhibits the action of androgens, and gossypol prevents spermatogenesis

Cyro-SEM image of a fibrillar gel formed by denaturing of lysozyme in an organic solvent Reprinted with permission from H. Van et al., Biomacromolecules, 7,1776. Copyright American Chemical Society

Cys spacing of common conotoxin frameworks.

Cys-tagged proteins conjugated to Ad-liposomes retain their functional activity, .

Cys2-His2 zinc finger DNA-binding proteins contain multiple tandem repeats of zinc finger domains. A ribbon representation of a six-zinc-finger protein .

Cysmethynil induces autophagy and apoptosis through the specific inhibition of Icmt. for 48 h before subjected to propidium iodide labeling and flow DNA content analysis. This figure is reproduced from Ref. .

Cystamine may be used to label pbospbate groups, such as on nucleic acids, via a carbodiimide reaction using EDC. The resultant phosphoramidate linkage is a common way to modify oligonucleotides at the 5 end.

Cystamine may be used to label phosphate groups, such as at the 5 -end of oligonucleotides, via a carbodiimide reaction using EDC. The resultant phosphoramidate linkage is a common way to modify oligonucleotides at the 5 -end.

Cystamine may be used to label phosphate groups, such as on nucleic acids, via a carbodiimide reaction using EDC. The resultant phosphoramidate linkage is a common way to modify oligonucleotides at the 5 end.

Cystamine may be used to label protein carboxyiate groups using the water-soluble carbodiimide EDC.

Cystamine may be used to label protein carboxylate groups using the water-soluble carbodiimide EDC.



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