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Ubiquitination on an internal lysine and on the N-terminal residue of the target substrate. The first ubiquitin moiety is conjugated to a free a-NH2

Ubiquitinylation of proteins and degradation in the proteosome. Ubiquitin is initially activated by an enzyme El, whereby the C-terminal carboxyl group of ubiquitin becomes attached to an SH group of El via a thioester bond. The activated ubiquitin is then transferred from El-Ub to the ubiquitin-conjugating enzyme, E2. Finally, the ubiquitin is covalently attached to the target protein in a reaction catalyzed by the E3 ubiquitin ligase. Re-

Ubiquitinylation of the tumor suppressor protein p53. The attachment of ubiquitin molecules to p53 is catalyzed by the Hect-domain E3 ubiquitin ligase E6-AP which receives the activated ubiquitin from an E2 enzyme. An intermediate is formed where the ubiquitin is linked via a thioester bond to an active site cysteine of E6-AP. The E6 protein binds both to E6-AP and p53 and confers substrate specificity. C. cysteine K

Ubiquitous ring opening in water of N-phthalimide protecting groups.

UBS spectra of metal aerosol

UC concentrations in COz extracted from Atlantic Ocean surface waters

UC spectra of CaIn204

UC spectra, CIE and possible UC processes as function of and Ho contents in LiLa2. Adapted from Ref. by permission of John Wiley Sons Ltd

UC values of modern terrestrial plants

UC-NMR spectra . Purified solvents were used and the specta recorded at -60 C for CDClj and at room temperature for DMSO.

UC0O2 - C discharge curves.

UCAD results of a structure

UCBDCs after 10 days culturing

UCBDCs attached to scaffold surface were imaged by SEM after 2 week culturing

UCC process

UCCSD and UCCSD dissociation curves for H2O

UCCSD and UCCSD dissodation curves for H2O

UCLfor H2 AMC mixtures with 15 O2 volume concentration

UCP1 and UCP2 Expressions in WAT of Mice Fed Undaria Lipids and Control Diet. . Source

UCS ratio versus joint factor for combined data of POP and POP-cement mix specimens

UD-weave form of the fibers.

UDF-o-glucose.

UDM s mechanism for simulating the entrainment of dispersed tracer within the wakes of buildings . The incident puff is split into two puffs, one of which is entrained behind the building

UDM simulation of releases of tracer over a regular urban array and over flat terrain. The buildings enhance the dispersion of the tracer and retard its downwind advection

Udoteatrial



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