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Traditional binding site model compared to the Spider model of PPI. In traditional binding sites, the scaffold is part of the cavity and gives major contribution to the ligand binding affinity whereas at the protein-protein interface, the scaffold is more open to bulk solvent and plays the role of a connector of highly interacting chemical groups anchoring to hot spots of the cavity of one of the protein partner.

Traditional biocatalytic process for Ce-falexin.

Traditional C O bond formation strategies by carboxylic acid activation ,

Traditional cataljrtic cycle and proposed Pd cycle.

Traditional coal-to-liquid process

Traditional component model

Traditional compounding counter-rotating screw geometry.

Traditional Corporate Structure Exemplified by a Manufacturer of Packaging Machinery.

Traditional cross-coupling .

Traditional curricula driven by the structure of the discipline vs. curricula driven by applications and issues

Traditional Debye-Scherrer and Hull diffractometer

Traditional distillation process forthe synthesis of methyl acetate.

Traditional downstream process

Traditional drug discovery process.

Traditional duv-resist design using derivatives of polyhydroxystyrene. Monomer provides acid-labile pendent groups.

Traditional explanations of equatorial preference of alkyl-substituted cyclohexanes based on the 1,3-diaxial repulsive interactions or the presence of gauche interactions.

Traditional FCC vs. RxCat

Traditional filler box loading system

Traditional Fisher and Haworth projections of the ketose, fructose. Fructose can form a five-C ring called a furanose when the C-2 keto group reacts with the hydroxyl on C-5, as shown in a-D-fructofuranose.

Traditional Fisher projection of the two glucose sterioisomers—one reflects plane-polarized fight to the right dextrorotatory .

Traditional FMECA RPN Pareto diagram.

Traditional illustration of moisture hysteresis.

Traditional Incorrect Picture of C12O9

Traditional indole S5mthesis vs. dehydrogenative indole synthesis.

Traditional ionic EAP configuration



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