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T-antigen and 6,6 -difluoro-T-antigen MUCl glycopeptides obtained by solid-phase syntheses analogously to

T-B cell co-stimuli.

T-bag for solid-phase synthesis.

T-BDCP, dppe, and their electron-deficient derivatives.

T-beam construction used in most home roofing is also useful in stiffening the surfaces of plastics parts.

T-Binaphthyl, a Chiral Ligand

T-bone steak. Meat is a good source of phosphorus.

T-C diagram for the Nd H system constructed from differential thermal analysis data for the temperature range — 140 to 100 C. Key

T-celI selection. A population of thymocytes is subjected first to positive selection to remove cells that express T-cell receptors that will not bind to MHC proteins expressed by the individual organism. The surviving cells are then subjected to negative selection to remove cells that bind strongly to MHC complexes bound to self-peptides.

T-cell activation.

T-Cell Activatiou. The interaction between the T-cell receptor and a class I MHC-peptide complex results in the binding of CDS to the MHC protein, the recruitment of the protein tyrosine kinase Lck, and the phosphorylation of tyrosine residues in the ITAM sequences of the CD3 chains. After phosphorylation, the ITAM regions serve as docking sites for the protein kinase ZAP-70, which phosphorylates protein targets to transmit the signal.

T-cell dependent antibody response in immature cynomolgus monkeys at various postnatal ages. Keyhole limpet hemocyanin .

T-cell Differentiation in man. This figure summarizes the data presented in Sections 4.3.3 and 10.2 regarding the influence of well-defined thymic factors on T cell differentiation. The hypothesized sites of action of several thymic polypeptides are shown at the right.

T-Cell Receptor Class I MHC Complex. The T-cell receptor binds to a class I MHC protein containing a bound peptide. The T-cell receptor contacts both the MHC protein and the peptide as shown by surfaces exposed when the complex is separated . These surfaces are colored according to the chain that they contact.

T-cell receptor complex. The

T-Cell Receptor Complex. The T-cell receptor is associated with six CD3 molecules a CD3-y - CD3-e heterodimer, a CD3-5 - CD3-e heterodimer, and two chains of CD3-. Single ITAM sequences are present in the cytoplasmic domains of CD3-y, CD3-6, and CD3-e whereas three such sequences are found in each CD3- chain.

T-cell receptor cx and p genes undergo rearrangments much like immunoglobln genes see

T-cell receptor on the membrane of ER. The Ca -releasing channel is modulated by FKBP12, which binds to each of the four IP3R subunits. The increase of i in the cytoplasm activates calcineurin CN

T-cell receptor regions.

T-cell receptor stucture shown as a ribbon diagram. The anbgen-binding site is formed by CDR loops from the Va and Vp domain, as for antibodies.

T-Cell Receptor. This protein consists of an a chain and a P chain, each of which consists of two immunoglobulin domains and a membrane- spanning domain. The two chains are linked by a disulfide bond.

T-cell receptor. This protein consists of an u chain and a 3 chain, each of which consists of two immunoglobulin domains and a membrane-spanning domain. The two chains are linked by a disulfide bond. Drawn from lBD2.pdb.

T-Cell Selection. A population of thymocytes is subjected first to positive selection to remove cells that express T-cell receptors that will not bind to MHC proteins expressed by the individual organism. The surviving cells are then subjected to negative selection to remove cells that bind strongly to MHC complexes bound to self-peptides.

T-dependence of , TN is the temperature at which 205 if1 at the core exhibits a sharp peak.

T-dependence of the inverse diffusion constant, 1 D, from MD simulations. Comparison between MD simulations and NMR data .



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